Patent Number: 6,251,642

Title: Continuous process for preparing optically pure (S)-3-hydroxy-.gamma.-butyrolactone

Abstract: The present invention relates to a continuous process for preparing optically pure (S)-3-hydroxy-.gamma.-butyrolactone expressed by the following Formula 1 and more particularly, to a process which enables preparing optically pure (S)-3-hydroxy-.gamma.-butyrolactone economically in large quantities, by: (a) Preparing .alpha.-(1,4) linked oligosaccharide with adequate sugar distribution by reacting amylopectin which is easily available from natural product with enzyme under a specific condition; and (b) Performing oxidation, esterification and cyclization sequentially under a specific condition. ##STR1##

Inventors: Chun; Jongpil (Daejeon, KR), Cho; Yik-haeng (Daejeon, KR), Roh; Kyoung Rok (Daejeon, KR), Park; Young Mi (Daejeon, KR), Yu; Hosung (Daejeon, KR), Hwang, II; Dae (Daejeon, KR)

Assignee: Samsung Fine Chemicals, Co., Ltd.

International Classification: C07D 307/33 (20060101); C07D 307/00 (20060101); C12P 17/02 (20060101); C12P 17/04 (20060101); C12P 19/00 (20060101); C12P 7/40 (20060101); C12P 19/22 (20060101); C12P 19/14 (20060101); C12P 7/42 (20060101); C12P 017/04 (); C07D 307/33 ()

Expiration Date: 06/26/2018