Patent Number: 6,251,644

Title: Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer

Abstract: A method is presented for inactivating non-enveloped viruses that may be contaminating a biological solution or suspension by mixing the solution or suspension with a photosensitizer to form a mixture, adjusting the operating conditions of the mixture so as to increase the permeability of the viruses to the photosensitizer, and then irradiating the adjusted mixture.

Inventors: Sowemimo-Coker; Samuel O. (Arcadia, CA), Goodrich, Jr.; Raymond P. (Pasadena, CA)

Assignee: Baxter International, Inc.

International Classification: A61K 35/14 (20060101); A61K 35/18 (20060101); A61K 41/00 (20060101); A61L 2/00 (20060101); C07K 14/435 (20060101); C07K 14/755 (20060101); C12N 9/64 (20060101); C12N 7/04 (20060101); C12N 7/06 (20060101); A61K 38/00 (20060101); C12N 013/00 (); A01N 001/02 (); A01N 043/16 ()

Expiration Date: 06/26/2018