Patent Number: 6,251,663

Title: Recombinant eukaryotic plasmids containing allergen-gene and use thereof for the prevention and/or treatment of allergic diseases

Abstract: The present invention relates to recombinant eukaryotic plasmids comprising an eukaryotic expression vector and an allergen gene for the prevention and/or treatment of allergic diseases. When the recombinant vector containing allergen-gene administrate to an individual in need of such prevention and/or treatment by intramuscular injection, intranasal delivery or intratracheal delivery, the production of allergen-specific IgE synthesis can be inhibited. The invention also relates to the pharmaceutical compositions comprising the the recombinant vector for use in the the prevention and/or treatment of allergic diseases and the production of allergen-specific IgE synthesis. A method for the prevention and/or treatment of allergic diseases is also provided.

Inventors: Hsu; Ching-Hsiang (Kao-Hsiung, TW), Chua; Kaw-Yan (Taipei, TW), Tao; Mi-Hua (Hsien, TW), Hsieh; Kue-Hsiung (Taipei, TW)

Assignee: Jen Wen Co., Ltd.

International Classification: A61K 39/35 (20060101); A61K 031/70 (); C12N 015/74 ()

Expiration Date: 06/26/2018