Patent Number: 6,251,864

Title: Peptides and compounds that bind to a receptor

Abstract: Described are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics.

Inventors: Dower; William J. (Menlo Park, CA), Barrett; Ronald W. (Saratoga, CA), Cwirla; Steven E. (Menlo Park, CA), Gates; Christian M. (Santa Cruz, CA), Schatz; Peter J. (Mountain View, CA), Balasubramanian; Palaniappan (Cupertino, CA), Wagstrom; Christopher R. (Los Altos, CA), Hendren; Richard Wayne (Cary, NC), Deprince; Randolph B. (Raleigh, NC), Podduturi; Surekha (San Jose, CA), Yin; Qun (Sunnyvale, CA)

Assignee: Glaxo Group Limited

International Classification: A61K 38/00 (20060101); A61K 38/02 (20060101); C07K 7/00 (20060101); C07K 5/00 (20060101); A61K 038/00 (); A61K 038/02 (); C07K 005/00 (); C07K 007/00 ()

Expiration Date: 06/26/2018