Patent Number: 6,251,865

Title: Insulin-like growth factor agonist molecules

Abstract: Compounds are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist compounds, which include peptides, are useful to increase serum and tissue levels of active IGFs in a mammal.

Inventors: Clark; Ross G. (Auckland, NZ), Lowman; Henry B. (El Granada, CA), Robinson; Iain C. A. F. (St. Albans, GB)

Assignee: Genentech, Inc.

International Classification: A61K 38/30 (20060101); C07K 7/08 (20060101); C07K 7/00 (20060101); C07K 14/435 (20060101); C07K 14/47 (20060101); A61K 38/00 (20060101); A61K 038/08 (); A61K 038/10 (); C07K 007/06 (); C07K 007/08 (); C07H 021/04 ()

Expiration Date: 06/26/2018