Patent Number: 6,251,873

Title: Antisense compounds to CD14

Abstract: The present invention relates to an oligonucleotide and derivatives, hybridizable with or being complementary to at least a part of a gene encoding human CD14; and to pharmaceutical compositions, comprising the oligonucleotide or derivatives thereof as effective ingredient; and is utilisable of cure of systemic inflammatory response sydorome, etc., by the use of the pharmaceutical composition.

Inventors: Furusako; Shoji (Tokyo, JP), Horisawa; Yoshifumi (Tokyo, JP), Kusuyama; Takeshi (Tokyo, JP)

Assignee: Mochida Pharmaceutical Co., Ltd.

International Classification: C07K 14/435 (20060101); C07K 14/705 (20060101); C12N 15/11 (20060101); A61K 38/00 (20060101); A61K 048/00 (); C12Q 001/68 (); C07H 021/04 ()

Expiration Date: 06/26/2018