Patent Number: 6,251,900

Title: Heterocyclic compounds and antitumor agent containing the same as active ingredient

Abstract: Heterocyclic compounds in which s-triazine or pyrimidine is substituted with benzimidazole and morpholine and which are represented by the Formula I or phermaceutically acceptable acid addition salts thereof: ##STR1## wherein X and Y respectively represent nitrogen atom or one of them represents nitrogen atom and the other represents C--R.sub.7 wherein R.sub.7 represents hydrogen or halogen atom; R.sub.1, R.sub.2, R.sub.4, R.sub.5 and R.sub.6 represent hydrogen atom or C.sub.1 -C.sub.6 alkyl; R.sub.3 represents morpholino, piperidino, piperazinyl, thiomorpholino, benzimidazolyl, cyano or the like.

Inventors: Kawashima; Seiichiro (Tokyo, JP), Matsuno; Toshiyuki (Tokyo, JP), Yaguchi; Shinichi (Tokyo, JP), Watanabe; Tetsuo (Tokyo, JP), Inaba; Masahiro (Tokyo, JP)

Assignee: Zenyaku Kogyo Kabushiki Kaisha

International Classification: C07D 413/14 (20060101); C07D 401/00 (20060101); C07D 403/00 (20060101); C07D 401/14 (20060101); C07D 403/14 (20060101); C07D 403/04 (20060101); C07D 491/10 (20060101); C07D 491/00 (20060101); C07D 413/00 (20060101); A61K 031/537 (); A61P 035/00 (); C07D 413/14 ()

Expiration Date: 06/26/2018