Patent Number: 6,251,907

Title: 1-(aryloxyalkyl)-4-(heteroaryl) piperazines and related compounds useful as antipsychotics and analgesics

Abstract: Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

Inventors: Strupczewski; Joseph T. (Flemington, NJ), Helsley; Grover C. (Stockton, NJ), Glamkowski; Edward J. (Warren, NJ), Chiang; Yulin (Covent Station, NJ), Bordeau; Kenneth J. (Kintnersville, PA), Nemoto; Peter A. (Raritan, NJ), Tegeler; John J. (Bridgewater, NJ)

Assignee: Aventis Pharmaceuticals Inc.

International Classification: C07D 403/12 (20060101); C07D 275/06 (20060101); C07D 231/56 (20060101); C07D 413/00 (20060101); C07D 471/00 (20060101); C07D 231/00 (20060101); C07D 413/14 (20060101); C07D 413/04 (20060101); C07D 413/12 (20060101); C07D 275/00 (20060101); C07F 7/00 (20060101); C07D 417/04 (20060101); C07D 417/14 (20060101); C07D 471/04 (20060101); C07D 401/00 (20060101); C07D 403/00 (20060101); C07D 401/04 (20060101); C07D 401/14 (20060101); C07F 7/18 (20060101); C07D 401/12 (20060101); C07D 417/00 (20060101); A61K 031/495 (); A61P 025/18 (); C07D 403/04 ()

Expiration Date: 06/26/2018