Patent Number: 6,251,923

Title: Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation

Abstract: The invention relates to new hydroxyindoles of the Formula, ##STR1## their use as inhibitors of phosphodiesterase 4 and processes for their preparation.

Inventors: Hofgen; Norbert (Ottendorf-Okrilla, DE), Egerland; Ute (Radebeul, DE), Poppe; Hildegard (Dresden, DE), Marx; Degenhard (Radebeul, DE), Szelenyi; Stefan (Schwaig, DE), Kronbach; Thomas (Radebeul, DE), Polymeropoulos; Emmanuel (Frankfurt, DE), Heer; Sabine (Radebaul, DE)

Assignee: Arzneimittelwerk Dresden GmbH

International Classification: C07D 209/22 (20060101); C07D 209/24 (20060101); C07D 209/00 (20060101); C07D 401/00 (20060101); C07D 401/12 (20060101); A61K 031/443 (); C07D 401/06 ()

Expiration Date: 06/26/2018