Patent Number: 6,251,935

Title: Treatment of migraine by administration of .alpha.-lipoic acid or derivatives thereof

Abstract: The invention relates to the use of racemic .alpha.-lipoic acid or its enantiomers or pharmaceutically acceptable salts, amides, esters or thioesters thereof, in reduced or oxidized form, as active ingredient in the prevention or the acute or chronic treatment of migraine.

Inventors: Schoenen; Jean (Beaufays-Chaudfontaine, BE), Engel; Jurgen (Alzenau, DE), Wessel; Klaus (Bad Vilbel, DE), Peukert; Manfred (Warstein, DE), Lobisch; Michael (Reichelsheim/Blofeld, DE), Borbe; Harald (Mainz, DE)

Assignee: ASTA Medica Aktiengesellschaft

International Classification: A61K 31/403 (20060101); A61K 31/405 (20060101); A61K 31/385 (20060101); A61K 31/48 (20060101); A61K 031/385 ()

Expiration Date: 06/26/2018