Patent Number: 6,252,024

Title: Fluorescent N-alkylated acrylamide copolymers and optical pH sensors

Abstract: A water-insoluble copolymer which is composed of (a) from 39.9 to 60% by weight of N,N-dimethylacrylamide or N,N-dimethylmethacrylamide; (b) from 60 to 39.9% by weight of N-alkylated acryl amides or N-alkylated methacryl amides; (c) from 0.1 to 0.7% by weight of a proton-sensitive fluorophore which is covalently bonded to the copolymer; and (d) from 0 to 20% by weight of a diolefinic crosslinking component. The copolymer is used in the form of a membrane on a transparent support material as an optical sensor for ionic strength-independent pH value determination.

Inventors: Barnard; Steven Mark (Wellesley Hills, MA), Berger; Joseph (Muttenz, CH), Rouilly; Marizel (Gipf-Oberfrick, CH), Waldner; Adrian (Allschwil, CH)

Assignee: Novartis AG

International Classification: C08F 220/56 (20060101); C08F 220/00 (20060101); G01N 21/64 (20060101); G01N 33/84 (20060101); C08F 226/06 (); C08F 224/00 ()

Expiration Date: 06/26/2018