Patent Number: 6,252,056

Title: Human lysophosphatidic acid receptor and use thereof

Abstract: (1) A human lysophosphatidic acid (human LPA) receptor, (2) a method for screening an antagonist or agonist, comprising using a human LPA receptor protein, (3) an LPA inhibitor comprising the human LPA receptor, (4) a method for producing the human LPA receptor, (5) a monoclonal or polyclonal antibody against the human LPA receptor, (6) a cDNA encoding the human LPA receptor, (7) a replication or expression vector carrying the above cDNA, and (8) a host cell transformed with the above replication or expression vector.

Inventors: Fukushima; Daikichi (Osaka, JP), Nakade; Shinji (Osaka, JP), Haga; Hisanori (Osaka, JP)

Assignee: Ono Pharmaceutical Co., Ltd.

International Classification: C07K 14/435 (20060101); C07K 14/705 (20060101); A61K 38/00 (20060101); C07H 021/02 (); C12P 021/06 (); C12P 019/34 (); C12N 001/20 (); C12M 001/02 ()

Expiration Date: 06/26/2018