Patent Number: 6,252,067

Title: Method of preparing oxoquazepam

Abstract: A method of preparing oxoquazepam which comprises reacting 2,2,2-trifluoroethyl trifluoromethanesulfonate with 7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one in tetrahydrofuran or ethyl acetate in the presence of potassium carbonate under reflux. According to the method of the present invention, high purity oxoquazepam can be manufactured in high yields.

Inventors: Ogawa; Masaki (Yachiyo, JP), Kita; Fumio (Yachiyo, JP)

Assignee: SSP Co., Ltd.

International Classification: C07D 243/24 (20060101); C07D 243/00 (20060101); C07D 243/26 ()

Expiration Date: 06/26/2018