Patent Number: 6,252,084

Title: 1H-indole-3-acetamide sPLA2 inhibitors

Abstract: A class of novel 1H-indole-3-acetamides is disclosed together with the use of such indole compounds for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock.

Inventors: Bach; Nicholas J. (Indianapolis, IN), Dillard; Robert D. (Zionsville, IN), Draheim; Susan E. (Indianapolis, IN), Hermann; Robert B. (Indianapolis, IN), Schevitz; Richard W. (Indianapolis, IN)

Assignee: Eli Lilly and Company

International Classification: C07D 209/22 (20060101); C07D 209/24 (20060101); C07D 209/00 (20060101); C07D 209/30 (20060101); C07D 401/06 (20060101); C07D 401/00 (20060101); C07F 9/572 (20060101); C07F 9/00 (20060101); C07F 009/38 (); C07D 209/10 (); C07D 209/14 (); C07D 403/06 ()

Expiration Date: 06/26/2018