Patent Number: 6,252,085

Title: Production of amide derivatives and intermediates therefor

Abstract: A method for producing an amide derivative of the formula [XV] ##STR1## wherein each-symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof. The production method of the present invention is extremely easy and simple as compared to the conventional methods, and enables effective production of compound [XV] at high yields, which includes compound [XVI] having an HIV protease inhibitory action. In addition, the novel intermediates of the present invention are extremely useful as intermediates for producing not only the aforementioned compound [XVI] but also compounds useful as X-ray contrast media.

Inventors: Inaba; Takashi (Takatsuki, JP), Yamada; Yasuki (Takatsuki, JP)

Assignee: Japan Tobacco Inc.

International Classification: C07C 319/00 (20060101); C07C 319/14 (20060101); C07D 263/14 (20060101); C07D 217/00 (20060101); C07D 413/00 (20060101); C07D 263/00 (20060101); C07D 217/26 (20060101); C07D 321/00 (20060101); C07D 321/06 (20060101); C07D 413/04 (20060101); C07C 323/25 (20060101); C07C 323/00 (20060101); C07C 323/42 (20060101); C07D 263/08 ()

Expiration Date: 06/26/2018