Patent Number: 6,252,088

Title: Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives

Abstract: A process for preparing a compound represented by general formulae (5) and (6) in the following reaction scheme or salts thereof, wherein R.sup.1 represents a protective group for a nitrogen atom; R.sup.2 represents a methanesulfonyl group or p-toluenesulfonyl group; R.sup.3 represents a hydrogen atom, an aralkyl group, or an alkyl group having 1 to 6 carbon atoms; and X represents a halogen atom. ##STR1## The above process is useful as an industrial process for preparing intermediates of anticoagulant aromatic amidine derivatives described in Japanese Patent Application Laid-Open (kokai) No. 208946/1993.

Inventors: Yokoyama; Yukio (Tokyo, JP), Kobayashi; Tatsuya (Tokyo, JP), Koyama; Takeo (Tokyo, JP)

Assignee: Daiichi Pharmaceutical Co., Ltd.

International Classification: C07C 253/00 (20060101); C07C 255/50 (20060101); C07C 255/00 (20060101); C07D 207/12 (20060101); C07D 207/00 (20060101); C07C 253/30 (20060101); C07C 255/52 (20060101); C07D 207/12 ()

Expiration Date: 06/26/2018