Patent Number: 6,252,090

Title: Compounds having activity as inhibitors of cytochrome P450RAI

Abstract: Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##

Inventors: Vasudevan; Jayasree (Anaheim, CA), Johnson; Alan T. (San Diego, CA), Huang; Dehua (San Diego, CA), Chandraratna; Roshantha A. (Laguna Hills, CA)

Assignee: Allergan Sales, Inc.

International Classification: A61K 31/192 (20060101); A61K 31/185 (20060101); A61K 31/195 (20060101); A61K 31/382 (20060101); A61K 31/352 (20060101); A61K 31/353 (20060101); A61K 31/47 (20060101); A61K 31/4747 (20060101); A61K 31/472 (20060101); C07D 215/14 (20060101); C07C 59/00 (20060101); C07D 409/00 (20060101); C07D 215/00 (20060101); C07D 333/00 (20060101); C07D 217/00 (20060101); C07D 311/00 (20060101); C07D 311/96 (20060101); C07D 221/20 (20060101); C07C 59/72 (20060101); C07D 409/06 (20060101); C07C 65/28 (20060101); C07D 521/00 (20060101); C07C 65/00 (20060101); C07D 335/06 (20060101); C07D 333/40 (20060101); C07D 335/04 (20060101); C07D 217/04 (20060101); C07D 221/00 (20060101); C07D 335/00 (20060101); C09B 029/22 (); C07D 335/06 (); C07D 495/10 ()

Expiration Date: 06/26/2018