Patent Number: 6,252,096

Title: Tetrafluoroazidoaniline and method of making and using the same

Abstract: The invention is directed to a novel compounds comprising 4-azidotetrafluoroaniline and the alkyl, acyl and sulfonamide derivatives thereof and to methods of making and using the same. The novel compounds are useful as a photoaffinity probe to study protein structure and function. Two methods for preparing 4-azidotetrafluoroaniline are disclosed, each employing a stable carbamate intermediate from which the 4-azidotetrafluoroaniline is derived.

Inventors: Spielmann; Hans Peter (Lexington, KY), Chehade; Kareem Abdel Hassan (Lex, KY)

Assignee: University of Kentucky Research Foundation

International Classification: C07C 311/44 (20060101); C07C 247/16 (20060101); C07C 247/00 (20060101); C07C 311/00 (20060101); C07C 247/10 ()

Expiration Date: 06/26/2018