Patent Number:
6,252,096
Title:
Tetrafluoroazidoaniline and method of making and using the same
Abstract:
The invention is directed to a novel compounds comprising 4-azidotetrafluoroaniline and the alkyl, acyl and sulfonamide derivatives thereof and to methods of making and using the same. The novel compounds are useful as a photoaffinity probe to study protein structure and function. Two methods for preparing 4-azidotetrafluoroaniline are disclosed, each employing a stable carbamate intermediate from which the 4-azidotetrafluoroaniline is derived.
Inventors:
Spielmann; Hans Peter (Lexington, KY), Chehade; Kareem Abdel Hassan (Lex, KY)
Assignee:
University of Kentucky Research Foundation
International Classification:
C07C 311/44 (20060101); C07C 247/16 (20060101); C07C 247/00 (20060101); C07C 311/00 (20060101); C07C 247/10 ()
Expiration Date:
06/26/2018