Patent Number: 6,252,105

Title: Synthesis of low-fluoride organic compounds

Abstract: Organic compounds, e.g. fluorinated organic compounds such as fluorinated carboxylic acids or fluorinated carboxylic acid chlorides, may contain small amounts of carboxylic acid fluorides, hydrogen fluoride or hydrolyzable fluoride, which during the preparation of derivatives of the fluorinated organic compounds, for example by esterification, may yield corrosive fluorides or hydrogen fluoride. The invention is a method for the synthesis and/or purification of preferably fluorinated organic compounds such as carboxylic acids, carboxylic acid chlorides and derivatives such as esters thereof, starting from corresponding carboxylic acid chlorides containing acid fluorides or hydrolyzable fluoride, and alcohols under the catalytic action of "onium" salts of carboxylic acids, to obtain products which have a low fluoride content. Alternatively, an inorganic oxide adsorbent is utilized. The method is especially suitable for the synthesis of esters of trifluoroacetic acid, chlorodifluoroacetic acid, trifluoroacetoacetic acid and/or difluoroacetoacetic acid.

Inventors: Braun; Max (Wedemark, DE), Eicher; Johannes (Oedheim, DE), Janssens; Francine (Vilvoorde, BE), Eichholz; Kerstin (Langenhagen, DE), Palsherm; Stefan (Barsinghausen, DE)

Assignee: Solvay Fluor und Derivate GmbH

International Classification: C07C 53/00 (20060101); C07C 51/58 (20060101); C07C 51/47 (20060101); C07C 51/42 (20060101); C07C 51/64 (20060101); C07C 67/56 (20060101); C07C 67/58 (20060101); C07C 67/00 (20060101); C07C 53/18 (20060101); C07C 67/14 (20060101); C07C 069/63 ()

Expiration Date: 06/26/2018