Patent Number: 6,252,112

Title: Process for the preparation of an enantiomer of a (1R, 4S) or (1S, 4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene derivative

Abstract: A novel process for the preparation of (1S, 4R)- or (1R, 4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2 -cyclopentene-1-methanol of the formula ##STR1## is described.

Inventors: Bernegger; Christine (Munster, CH), Urban; Eva Maria (Visp, CH), Birch; Olwen Mary (Visp, CH), Burgdorf; Kurt (Ried-Brig, CH), Brux; Frank (Raron, CH), Etter; Kay-Sara (Niedergampel, CH), Bossard; Pierre (Onex, CH), Brieden; Walter (Brig-Glis, CH), Duc; Laurent (Chermignon, CH), Gordon; John (Naters, CH), O'Murchu; Colm (Visp, CH), Guggisberg; Yves (Sierre, CH)

Assignee: Lonza A.G.,

International Classification: C07C 233/23 (20060101); C07C 233/00 (20060101); C07C 271/00 (20060101); C07C 271/24 (20060101); C07D 209/94 (20060101); C07D 209/00 (20060101); C12P 13/00 (20060101); C12P 17/18 (20060101); C12P 13/02 (20060101); C07C 231/18 ()

Expiration Date: 06/26/2018