Patent Number: 6,252,114

Title: Process for preparing novel biologically active synthetic molecule 4-(p-methoxyphenyl)-2-amino-butane

Abstract: The invention provides a process for the preparation of 4-(p-methoxyphenyl)-2-aminobutane represented by structural formula (1) as shown herein below: ##STR1## [C.sub.11 H.sub.17 ON=4-(p-methoxy phenyl)-2-amino butane] said process comprising the steps of, (a) isolating a phenolic compound 4-hydroxyphenyl)-butan-2-ol from the leaves of Taxus wallichiana by known methods, (b) treating the phenolic compound in aqueous mineral acid to obtain a phenolic halide derivative, (c) converting the phenolic halide derivative into its methyl ether by treating it with a methating agent, (d) reacting the methyl ether halide with azide to obtain an azido derivative, and (e) hydrogenating the azido compound to obtain 4-(p-methoxyphenyl)-2-aminobutane.

Inventors: Chattopadhyay; Sunil Kumar (Lucknow, IN), Sashidhara; Koneni Venkata (Lucknow, IN), Tripathi; Vinayak (Lucknow, IN), Tripathi; Arun Kumar (Lucknow, IN), Prajapati; Veena (Lucknow, IN), Kumar; Sushil (Lucknow, IN)

Assignee: Council of Scientific and Industrial Research

International Classification: C07C 217/62 (20060101); C07C 217/00 (20060101); C07C 43/00 (20060101); C07C 43/225 (20060101); C07C 207/00 ()

Expiration Date: 06/26/2018