Patent Number: 6,252,116

Title: Intermediates useful in a process for synthesizing COX-2 inhibitors

Abstract: The invention encompasses a process for making compounds of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##

Inventors: Corley; Edward G. (Old Bridge, NJ), Davies; Ian W. (Princeton, NJ), Larsen; Robert D. (Bridgewater, NJ), Pye; Philip J. (Guttenberg, NJ), Rossen; Kai (Westfield, NJ)

Assignee: Merck & Co., Inc.

International Classification: C07C 251/30 (20060101); C07C 251/00 (20060101); C07D 213/00 (20060101); C07D 213/61 (20060101); C07C 211/00 ()

Expiration Date: 06/26/2018