Patent Number: 6,254,830

Title: Magnetic focusing immunosensor for the detection of pathogens

Abstract: A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and exciting fibers and means for detecting, collecting and measuring fluorescent signals in communication with the collecting fiber. The probe and the collecting and exciting fibers are configured to focus paramagnetic microspheres attached to antigen/antibody/optically labeled complexes in a predetermined pattern in the field of view of the collecting fiber while blocking background interference.

Inventors: Pivarnik; Philip (Narragansett, RI), Cao; He (Kingston, RI), Letcher; Stephen V. (Kingston, RI), Rand; A. Garth (Kingston, RI)

Assignee: The Board of Governors for Higher Education, State of Rhode Island and Providence Plantations

International Classification: G01N 21/64 (20060101); G01N 021/64 (); G01N 033/553 (); G01N 033/53 (); C12M 001/00 ()

Expiration Date: 07/03/2018