Patent Number: 6,254,852

Title: Porous inorganic targeted ultrasound contrast agents

Abstract: Targeted ultrasound contrast agents are described. The contrast agents are porous particles of an inorganic material containing an entrapped gas or liquid and having an average particle diameter of about 0.05 to 500 microns. The outer surfaces of the particles incorporate a targeting ligand to target delivery of the contrast agent.

Inventors: Glajch; Joseph L (Nashua, NH), Carpenter, Jr.; Alan P. (Carlisle, MA), Cheesman; Edward H. (Lunenberg, MA)

Assignee: Dupont Pharmaceuticals Company

International Classification: A61K 49/22 (20060101); A61B 008/00 ()

Expiration Date: 07/03/2018