Patent Number: 6,254,853

Title: Water soluble pro-drugs of propofol

Abstract: This invention provides esters of propofol (2,6,-diisoprophenol). The propofol esters are soluble in water and metabolize rapidly to propofol in the body. The propofol esters are useful as pro-drugs for the same indications as propofol. This invention also provides methods of treating neurodegenerative diseases by administering as effective amount of propofol.

Inventors: Hendler; Sheldon S. (La Jolla, CA), Sanchez; Robert A. (Riverton, UT), Zielinski; Jan (San Diego, CA)

Assignee: Vyrex Corporation

International Classification: C07C 39/00 (20060101); C07C 39/26 (20060101); C07C 39/27 (20060101); C07C 69/017 (20060101); C07C 69/00 (20060101); C07F 9/12 (20060101); C07F 9/00 (20060101); A61K 009/12 (); A61K 009/10 (); A61K 009/14 ()

Expiration Date: 07/03/2018