Patent Number: 6,254,863

Title: Non-virulent Porphyromonas gingivalis mutant

Abstract: A non-virulent, recA defective mutant of Porphyromonas gingivalis. The Porphyromonas gingivalis strain which is deposited at ATCC under accession number 202109. Also a method of decreasing the growth rate or reproduction rate of Porphyromonas gingivalis in a mammal comprising the step of administering to the mammal at least one dose of Porphyromonas gingivalis according to the present invention. Further, a method of preventing or treating a Porphyromonas gingivalis infection such as periodontitis in a mammal comprising the step of administering to the mammal at least one dose of Porphyromonas gingivalis according to the present invention. Also, a pharmaceutical composition comprising a non-virulent, recA defective mutant of Porphyromonas gingivalis.

Inventors: Fletcher; Hansel M. (Loma Linda, CA)

Assignee: Loma Linda University

International Classification: C07K 14/195 (20060101); A01N 063/00 (); A61K 048/00 (); A61K 039/02 (); A61K 039/295 (); A61K 045/00 ()

Expiration Date: 07/03/2018