Patent Number: 6,254,870

Title: Thrombopoietin: IL-3 fusion protein

Abstract: The present invention relates to variants of human c-mpl ligands (thrombopoietin) with activity on hematopoietic differentiation and expansion.

Inventors: Staten; Nicholas R. (St. Louis, MO), Favara; Jean P. (Ballwin, MO), Kahn; Larry E. (St. Louis, MO), Pegg; Lyle E. (Ballwin, MO), McKearn; John P. (Glencoe, MO), Baum; Charles M. (Evanston, IL)

Assignee: G. D. Searle & Co.

International Classification: C07K 14/435 (20060101); C07K 14/52 (20060101); C07K 19/00 (20060101); C07K 14/54 (20060101); A61K 38/00 (20060101); A61K 48/00 (20060101); C12N 015/19 (); C07K 014/475 ()

Expiration Date: 07/03/2018