Patent Number: 6,254,879

Title: Methods of treating protozoal diseases

Abstract: The invention concerns a new pharmaceutical agent for oral or topical administration in the treatment of protozoal diseases, in particular of leishmaniasis, which contains as the active substance one or several compounds having the general formula I ##STR1## in which R.sup.1 is a saturated or monounsaturated or polyunsaturated hydrocarbon residue with 12 to 20 C atoms and R.sup.2, R.sup.3 and R.sup.4 denote independently of one another hydrogen, a C.sub.1 -C.sub.5 alkyl group, a C.sub.3 -C.sub.6 cycloalkyl group or a C.sub.1 -C.sub.5 hydroxyalkyl group whereby two of the residues R.sup.2, R.sup.3 and R.sup.4 can together form a C.sub.2 -C.sub.5 alkylene group which, if desired, can be substituted with an --O--, --S-- or NR.sup.5 group, in which R.sup.5 is hydrogen, a C.sub.1 -C.sub.5 alkyl group, a C.sub.3 -C.sub.6 cycloalkyl group or a C.sub.1 -C.sub.5 hydroxyalkyl group as well as, if desired the usual pharmaceutical auxiliary, diluting, carrier or/and filling substances.

Inventors: Eibl; Hansjorg (Bovenden-Eddigehausen, DE), Unger; Clemens (Gottingen, DE), Engel; Jurgen (Alzenau, DE)

Assignee: Max-Planck-Gessellschaft zun Forderung der Wissenschaften e.V.

International Classification: A01N 59/26 (20060101); A61K 6/00 (20060101); A61K 006/00 (); A61N 025/00 (); A01N 059/26 ()

Expiration Date: 07/03/2018