Patent Number: 6,255,292

Title: Purine nucleotide analogues, pharmaceutical compositions thereof, and methods of improving cardiac functions

Abstract: The specification discloses purine nucleotide analogues which modulate cardiac muscle contractility and possess vasodilator activity. In addition, related methods of administration and the identity of receptors that bind these compounds are disclosed.

Inventors: Liang; Bruce T. (Merion Station, PA)

Assignee: The Trustees of the University of Pennsylvania

International Classification: C07H 19/20 (20060101); C07F 9/00 (20060101); C07F 9/6561 (20060101); C07K 14/435 (20060101); C07F 9/6558 (20060101); C07H 19/00 (20060101); C07K 14/705 (20060101); A61K 031/70 (); C07H 019/20 ()

Expiration Date: 07/03/2018