Patent Number: 6,255,298

Title: Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases

Abstract: Salicylanilide derivatives which are macrophagescavenger receptor antagonists are provided. Methods of treating cardiovascular disease comprising administration of the present compounds are also provided. The present compounds inhibit lipid accumulation within macrophage-derived foam cells.

Inventors: Lysko; Paul G. (Downingtown, PA), Weinstock; Joseph (Wayne, PA)

Assignee: SmithKline Beecham Corporation

International Classification: A61K 031/615 ()

Expiration Date: 07/03/2018