Patent Number: 6,294,649

Title: Method of cell inhibition using polypeptides derived from the venom of the Austrialian jumper ant Myrmecia pilosula

Abstract: An isolated polypeptide having cytotoxic activity comprising the amino acid sequence of Pilosulin 1 shown in the figure, and active portion thereof, or a functionally equivalent amino acid sequence thereof, and a method of inhibiting the growth of a cell comprising exposing the cell to an effective amount of Pilosulin 1 shown in the figure, and active portion thereof, or a functionally equivalent amino acid sequence thereof, such that the growth of the cell is inhibited.

Inventors: Donovan; Gregory (Berowra Heights, AU), Baldo; Brian (Pymble, AU)

Assignee: Northern Sydney Area Health Service

International Classification: C07K 14/435 (20060101); A61K 38/00 (20060101); A61K 038/16 ()

Expiration Date: 09/25/2018