Patent Number: 6,294,664

Title: Synthesis of oligonucleotides

Abstract: Synthetic processes are provided for the solution phase synthesis ofoligonucleotides, especially phosphorothioate oligonucleotides, andintermediate compounds useful in the processes. Intermediates havingstructure (I) are prepared in accordance with preferred embodiments.##STR1##

Inventors: Ravikumar; Vasulinga (Carlsbad, CA), Cole; Douglas L. (San Diego, CA)


International Classification:

Expiration Date: 09/25/2013