Patent Number: 6,294,673

Title: Process for preparing nifedipine

Abstract: The invention relates to a process for the preparation of nifedipine by the reaction of methyl 2-(2-nitrobenzylidene)acetoacetate and methyl 3-aminocrotonate and the use of the nifedipine thus prepared for the production of a medicament.

Inventors: Berwe; Mathias (Sprockhovel, DE), Diehl; Herbert (Leverkusen, DE), Rittner; Karl (Odenthal, DE), Wahl; Karl-Heinz (Odenthal, DE), Wirges; Hans-Peter (Krefeld, DE)

Assignee: Bayer Aktiengesellschaft

International Classification: A61K 31/4422 (20060101); C07D 211/00 (20060101); C07D 211/90 (20060101); C07D 211/04 (); C07D 211/08 ()

Expiration Date: 09/25/2018