Patent Number: 6,294,690

Title: Process for preparing a cyclic amino acid anticonvulsant compound

Abstract: An improved process for the preparation of a cyclic amino acid by a novelsynthesis is described where benzonitrile is treated with an alkali metaland an amine under Birch reduction conditions to generate in situ ananionic intermediate which is alkylated with an .alpha.-haloacetic acidmoiety which is subsequently converted to the desired product, as well asvaluable intermediates used in the process.

Inventors: Deering; Carl Francis (Fennville, MI), Mennen; Kenneth Earl (Holland, MI), Ramage; Robert (Edinburgh, GB)


International Classification:

Expiration Date: 09/25/2013