Patent Number: 6,294,695

Title: Aminobenzoic acid derivatives having anti-tumorigenic activity methods of making and using the same

Abstract: Haloacetoamido, benzoic acid derivatives having anti-tumorigenic activity are inclosed. Examples of the haloacetoamido, benzoic acid derivatives include 3-chloroacetoamido, benzoylurca, 3-bromoacctoamido, benzoylurea, 3-todoacetoamido, benzoylurca, ethyl-3-chloroacetoamido, benzoate, ethyl-3-bromoacetoamido, benzoate and ethyl-3-iodoacetoamido, benzoate. Intermediates for synthesizing the derivatives, along with method of making and using the derivatives, are also provided.

Inventors: Bekesi; George J (Edison, NJ), Jiang; Jian-Dong (New York, NY), Weisz; Imre (New York, NY), Roboz; John (Riverdale, NY), Holland; James F (Scarsdale, NY)

Assignee: Mount Sinai School of Medicine of the City University of New York

International Classification: C07C 275/00 (20060101); C07C 275/54 (20060101); C07C 237/28 ()

Expiration Date: 09/25/2018