Patent Number: 6,295,125

Title: Differential refractive index detector and liquid chromatograph equipped with the same

Abstract: To provide a differential refractive index detector free from fears for occurrence of personal errors in the judgement of stable condition and capable of performing highly efficient analysis operation, and a liquid chromatograph equipped with the detector. A differential refractive index detector provided with a reference cell, a sample cell, a light source for irradiating light on these two cells, a detecting part for detecting light transmitted through respective cells, and a signal processing part for applying predetermined processing to the output signal from the detecting part, which comprises means for sequentially performing an initial solution purge operation of purging the sample cell and the reference cell with an eluent by passing the eluent through the cells at the start of operation of said detector, a stabilizing solution purge operation of allowing the eluent purge of sample cell and reference cell to proceed and at the same time, confirming the stable condition thereof, and a stability confirming operation of confirming whether or not the detector has stabilized in an analysis capable condition by passing the eluent only through the sample cell, and means for announcing that the detector has stabilized in the analysis capable condition. According to the differential refractive index detector of the present invention, the processing from the initial solution purge operation to the stability confirming operation can be automated and a highly efficient analysis operation can be attained.

Inventors: Tokieda; Tsunemi (Kawasaki, JP), Nogami; Yukio (Kawasaki, JP), Inoue; Saburo (Kawaguchi, JP)

Assignee: Showa Denko K.K.

International Classification: G01N 30/74 (20060101); G01N 30/00 (20060101); G01N 21/41 (20060101); G01N 021/41 ()

Expiration Date: 09/25/2018