Patent Number: 6,306,829

Title: Modified VEGF oligonucleotides for treatment of skin disorders

Abstract: Disclosed are oligonucleotides complementary to VEGF-specific nucleic aciduseful in reducing the expression of VEGF. Also disclosed arepharmaceutical formulations containing such oligonucleotides useful fortreating various disorders associated with neovascularization andangiogenesis, and methods for treating psoriasis.

Inventors: Smyth; Adrienne P. (Charlton, MA), Robinson; Gregory S. (Acton, MA)


International Classification:

Expiration Date: 10/23/2013