Patent Number: 6,306,830

Title: Gene therapy for congestive heart failure

Abstract: The present invention relates to methods and compositions for enhancing cardiac function in mammalian hearts by inserting transgenes that increase .beta.-adrenergic responsiveness within the myocardium. The present invention can thus be used in the treatment of heart disease, especially congestive heart failure.

Inventors: Hammond; H. Kirk (La Jolla, CA), Insel; Paul A. (San Diego, CA), Ping; Peipei (Jeffersonville, IN), Post; Steven R. (Lexington, KY), Gao; Meihua (San Diego, CA)

Assignee: The Regents of the University of California

International Classification: C12N 9/88 (20060101); A61K 48/00 (20060101); A61K 048/00 (); A61K 035/00 (); C12N 015/63 (); C12N 007/00 ()

Expiration Date: 10/23/2018