Patent Number: 6,306,831

Title: Transplacental delivery of oligonucleotides

Abstract: This invention provides synthetic oligonucleotides that are useful for transplacental delivery, the oligonucleotides being DNA or RNA or both, preferably between 12-35 nucleotides in length, having a stabilized and charged backbone and at least one chemically modified base or sugar moiety, wherein the modified base or sugar moiety facilitates transplacental delivery.

Inventors: Roberts; Peter C. (Holliston, MA), Driver; Samuel E. (Brighton, MA)

Assignee: QIK Technologies, Inc.

International Classification: A01K 67/027 (20060101); C12N 15/11 (20060101); A61K 38/00 (20060101); A61K 048/00 ()

Expiration Date: 10/23/2018