Patent Number: 6,307,103

Title: Process for the preparation of 1,1,1-trifluoro-2-aminoalkanes

Abstract: An improved process for the preparation of a 1,1,1-trifluoro-2-aminoalkaneof formula I##STR1##whereinR.sup.1 represents an optionally substituted alkyl group;which comprises hydrogenating the corresponding oxime of formula II##STR2##wherein R.sup.1 has the meaning given above and the winding line indicatesthat the hydroxy group may be in the (E)- or (Z)-position with respect tothe trifluoromethyl group, in the presence of Raney nickel and a diluent;the improvement wherein is, that said reaction is carried out in a diluentselected from an alkanol, a cyclic ether and an aromatic hydrocarbon.

Inventors: Niedermann; Hans-Peter (Bubenheim, DE), Gutheil; Dieter (Bad Kreuznach, DE)


International Classification:

Expiration Date: 10/23/2013