Patent Number: 6,307,122

Title: Infection of human neural xenografts

Abstract: Immunocompromised or immunosuppressed non-primate chimeric mammalian hosts comprising a neuronal graft in the eye are provided for studying various events associated with humans. Particularly, the chimeric host may have solely human fetal neuronal xenografts or other fetal xenografts with other tissue, where the various tissues may be studied as to their response to a variety of agents, their response to pathogens or other diseased states, or their response to agents for the treatment of the various indications.

Inventors: Epstein; Leon G. (Rochester, NY), Del Cerro; Manuel (Pittsford, NY), Blumberg; Benjamin M. (Rochester, NY)


International Classification: A01K 67/027 (20060101); A01N 063/00 ()

Expiration Date: 10/23/2018