Patent Number: 6,309,355

Title: Method and assembly for performing ultrasound surgery using cavitation

Abstract: A method and assembly are provided which use cavitation induced by an ultrasound beam for creating a controlled surgical lesion in a selected treatment volume of a patient. First, a plurality of microbubbles are provided in the treatment volume. Preferably, the threshold for cavitation of microbubbles in the treatment volume is lowered compared with the threshold for cavitation in surrounding tissues. The expected location of the surgical lesion within the treatment volume may be previewed, and then the microbubbles in the treatment volume are cavitated with the ultrasound beam to create the controlled surgical lesion. Preferably, the creation of the surgical lesion at the expected lesion location is then verified. Using the method and assembly of the present invention, the cavitation threshold within the treatment volume is made predictable, and a low frequency ultrasound beam may be used to cavitate the microbubbles within the treatment volume without causing damage to surrounding tissues.

Inventors: Cain; Charles A. (Ann Arbor, MI), Fowlkes; J. Brian (Ann Arbor, MI)

Assignee: The Regents of the University of Michigan

International Classification: A61B 17/22 (20060101); A61M 37/00 (20060101); A61B 017/22 ()

Expiration Date: 10/30/2018