Patent Number: 6,309,648

Title: Protective epitopes of adenyl cyclase-haemolysin (AC-Hly), theirapplication to the treatment or to the prevention of bordetella infections

Abstract: The subject of the invention is amino acid sequences of the AC-Hly from B.pertussis. B. parapertussis and/or B. bronchiseptica, carrying epitopescapable of inducing a protective immune response against infection byBordetella. The subject of the invention is antibodies, especiallymonoclonal antibodies, directed against these epitopes.

Inventors: Betsou; Fotini (Paris, FR), Sebo; Peter (Prague, CZ), Guiso; Nicole (Paris, FR)


International Classification:

Expiration Date: 10/32013