Patent Number: 6,309,670

Title: Collagen-polysaccharide matrix for treatment of bone tumors

Abstract: A method of treatment for bone tumors comprising administering a matrix comprising collagen, a polysaccharide and a differentiation factor is provided. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent linkages to collagen.

Inventors: Heidaran; Mohammad (Los Gatos, CA), Spiro; Robert C. (Half Moon Bay, CA)

Assignee: Orquest, Inc.

International Classification: A61L 27/24 (20060101); A61L 27/00 (20060101); A61L 27/26 (20060101); A61F 2/00 (20060101); A61K 009/10 (); A61K 047/42 (); A61K 047/36 ()

Expiration Date: 10/30/2018