Patent Number: 6,309,701

Title: Fluorescent nanocrystal-labeled microspheres for fluorescence analyses

Abstract: Provided are a fluorescent microsphere comprised of a plurality of fluorescent nanocrystals operably bound to a polymeric microsphere, and a method of producing the fluorescent microspheres which comprises contacting the polymeric microsphere with a plurality of fluorescent nanocrystals under suitable conditions in which the fluorescent naocrystals become operably bound to the polymeric microsphere. Also provided is a method of using the fluorescent microspheres capable of determining the presence or absence of a predetermined number of analytes in a sample by contacting the sample with the fluorescent microspheres, and detecting the fluorescence signal pattern of excited fluorescent microspheres bound to one or more analytes of the predetermined number of analytes, if present in the sample.

Inventors: Barbera-Guillem; Emilio (Powell, OH)

Assignee: Bio-Pixels Ltd.

International Classification: A61K 49/00 (20060101); B05D 7/00 (20060101); B32B 9/04 (20060101); B32B 9/00 (20060101); H01L 29/02 (20060101); H01L 29/04 (20060101); A61K 049/00 (); B05D 007/00 (); B32B 009/00 (); B32B 009/04 (); H01L 029/04 ()

Expiration Date: 10/30/2018