Patent Number: 6,309,819

Title: Diagnostic and therapeutic system for Crohn's disease and Colitia ulcerosa

Abstract: The present invention relates to a diagnostic system for the detection of Crohn's disease and ulcerative colitis by means of nucleotide amplification reactions, in situ or in vitro which detection means are specific for the measles virus and are capable of distinguishing between the "wild" type and the attenuated measles virus strains. The invention further provides a use in the manufacture of a medicament for the treatment of Crohn's disease and/or ulcerative colitis which medicament comprises a suitable vector carrying antisense RNA to specific viral proteins which are consequently inhibited from being expressed in the host.

Inventors: Wakefield; Andrew Jeremy (Surrey TW9 4EB, GB)


International Classification: A61K 39/165 (20060101); A61K 39/155 (20060101); C12Q 1/68 (20060101); C12Q 1/70 (20060101); C12Q 001/70 (); C12Q 001/68 (); C12P 019/34 ()

Expiration Date: 10/30/2018