Patent Number: 6,309,821

Title: DNA encoding a PAC10 human homolog

Abstract: The present invention provides nucleotide and amino acid sequences for a novel PAC10 human homolog. The present invention also provides for antisense molecules, diagnostic molecules, genetically engineered expression vectors and host cells for the production of purified PAC10 homologs; antibodies, agonists, antagonists and inhibitors of the PAC10 human homolog; and pharmaceutical compositions and methods of treatment based on the polypeptide, its antibodies, ntagonists and inhibitors. The invention further provides diagnostic and theapeutic compositions for the detection and treatment of X-linked congenital abnormalities, such as centronuclear myopathy.

Inventors: Au-Young; Janice (Berkley, CA), Goold; Richard D. (San Francisco, CA)

Assignee: Incyte Genomics, Inc.

International Classification: C07K 14/435 (20060101); C07K 14/47 (20060101); C12Q 001/68 (); C12P 019/34 ()

Expiration Date: 10/30/2018