Patent Number: 6,309,835

Title: Methods for quantitating the efficacy of oral care products

Abstract: Methods are included for quantitating the efficacy of oral care products at dislodging cells from biofilm test surfaces or inhibit or delay the accumulation of cells on a test surface. More specifically, the inventive methods measure the effectiveness of compositions and appliances in a test environment that models biofilm surface orientations that are encountered on a tooth surface, i.e. interproximal and subgingival tooth surfaces. The use of test surfaces that are removably attachable to a tooth prosthesis allow a variety of different quantitative methods to be applied to determine the amount of cells removed or deposited in a biofilm.

Inventors: Iyer; Lokanathan M. (Bellevue, WA), Akridge; Robert E. (Seattle, WA), McInnes; James C. (Seattle, WA)

Assignee: Koninkiijke Philips Electronics N.V.

International Classification: C12Q 1/04 (20060101); C12Q 1/18 (20060101); C12Q 001/68 (); C12N 001/38 (); A61K 007/16 (); C07H 021/04 ()

Expiration Date: 10/30/2018