Patent Number: 6,309,882

Title: Antisense inhibition of replication protein a p70 subunit

Abstract: Compositions and methods are provided for modulating the expression of the replication protein A p70 subunit and for the treatment and diagnosis of diseases associated with replication protein A p70 subunit.

Inventors: Monia; Brett P. (LaCosta, CA), Basilion; James P. (Brookline, MA), Stanton, Jr.; Vincent P. (Belmont, MA)

Assignee: ISIS Pharmaceuticals, Inc.

International Classification: C12N 15/11 (20060101); C12N 9/14 (20060101); A61K 38/00 (20060101); C07H 021/02 (); C07H 021/04 (); C12Q 001/68 (); C12N 015/85 (); C12K 015/86 ()

Expiration Date: 10/30/2018