Patent Number: 6,309,999

Title: Process for the preparation of an immunoadsorbent matrix

Abstract: A process for the preparation of an immunoadsorbent matrix includespreparing polyvinyl alcohol beads by partially crosslinking polyvinylalcohol (PVA) with a crosslinking agent to provide polyvinyl alcohol beadswhich are at least partially crosslinked; coupling phenylalanine onto thepolyvinyl alcohol beads to obtain a --COOH functionality for thephenylalanine coupled polyvinyl alcohol beads; and activating the --COOHfunctionality for immobilizing heparin onto the phenylalanine coupledpolyvinyl alcohol beads.

Inventors: Sharma; Chandra P. (Pappanamcode, Trivandrum-695 018, IN), Hari; P. R. (Valiyavila, Thirumala, P.O. Trivandrum-695 006, IN), Paul; Willi (Ollur P.O. Trichur, IN)


International Classification:

Expiration Date: 10/32013